tenOever LaboratoryVirology · Host defense · RNA biology
Technologies

Electron microscopy

imaging and histology

Recorded terms: scanning electron microscopy; transmission electron microscopy

2020 · Cell · collaborative

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

A time-resolved phosphoproteomic survey of SARS-CoV-2-infected cells showing that infection acts mainly through signalling rather than protein abundance, activating casein kinase II and the p38 cascade while shutting down mitotic kinases, and converting that kinase profile into inhibitors with antiviral activity.