tenOever LaboratoryVirology · Host defense · RNA biology
Technologies

Expression screening of codon-optimised heterologous proteins

functional genomics and screening

Recorded terms: expression screening of codon-optimized proteins

2023 · Journal of Virology · lab-led

Archaeal Kink-Turn Binding Protein Mediates Inhibition of Orthomyxovirus Splicing Biology

Archaeal members of the L30 protein family, but not their orthologues from any other domain of life, block production of the spliced influenza A virus, influenza B virus and isavirus transcripts without measurably disturbing host splicing, identifying a shared and apparently noncanonical feature of orthomyxovirus splicing.